Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9517390 | 0.85 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL9515942 | 0.83 | CYP2D6 (0.36) | SLC6A4SIGMAR1ADRA2ASLC6A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9515917 | 0.81 | SLC6A2 (0.39) | SLC6A4SIGMAR1ADRA2ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9519827 | 0.81 | CYP2D6 (0.35) | SLC6A4SIGMAR1ADRA2ASLC6A2CYP2D6 | |
| SCHEMBL9519923 | 0.78 | HTR2A (0.44) | SIGMAR1ADRA2ATAAR1 | |
| Hydrochloric Acid SCHEMBL9517419 | 0.78 | SLC6A3 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9516334 | 0.78 | SLC6A3 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9518269 | 0.76 | HTR2A (0.43) | SIGMAR1ADRA2ATAAR1 | |
| SCHEMBL9518190 | 0.76 | ADRA2A (0.37) | SLC6A4SIGMAR1ADRA2ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9516362 | 0.76 | ADRA2A (0.46) | SIGMAR1ADRA2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2134347-A | — | — | None | — | — | JP | disclosed |
| EP-0361577-B1 | TETRAHYDRONAPHTHALENE AND INDANE DERIVATIVES | AKZO N.V. (NL) | 1993-05-05 | — | — | EP | disclosed |
| US-4980354-A | Tetrahydronaphthalene and indane derivatives | AKZO N.V. (NL) | 1990-12-25 | — | — | US | disclosed |
| JP-H02134347-A | TETRAHYDRONAPHTHALENE AND INDANE DERIVATIVE | AKZO NV | 1990-05-23 | — | — | JP | disclosed |
| EP-0361577-A1 | Tetrahydronaphthalene and indane derivatives | AKZO N.V. (NL) | 1990-04-04 | — | — | EP | disclosed |