Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519607 | 0.88 | EPHX2 (0.46) | MEN1CYP1A2CYP3A4KMT2A | |
| SCHEMBL9517022 | 0.82 | — | — | |
| SCHEMBL9515509 | 0.81 | NPC1 (0.50) | MEN1KMT2A | |
| SCHEMBL9519239 | 0.81 | BRD4 (0.44) | — | |
| SCHEMBL14819065 | 0.81 | ALDH1A1 (0.42) | MEN1CYP1A2CYP3A4KMT2A | |
| SCHEMBL9517267 | 0.79 | EPHX1 (0.51) | — | |
| SCHEMBL2382926 | 0.76 | MAPK1 (0.54) | KMT2A | |
| SCHEMBL14811677 | 0.76 | MAPT (0.50) | CYP1A2 | |
| SCHEMBL9566758 | 0.75 | NPC1 (0.57) | MEN1KMT2A | |
| SCHEMBL9527654 | 0.75 | CA12 (0.51) | CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |