Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516137 | 0.91 | HDAC3 (0.45) | TP53SMN1; SMN2L3MBTL1ALDH1A1SCN9A | |
| SCHEMBL9516006 | 0.81 | MEN1 (0.37) | — | |
| SCHEMBL9519589 | 0.80 | CXCR2 (0.54) | — | |
| SCHEMBL9566756 | 0.79 | RAB9A (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL9517022 | 0.79 | — | — | |
| SCHEMBL2421993 | 0.78 | NR4A2 (0.53) | — | |
| SCHEMBL9516029 | 0.78 | NPC1 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL9566749 | 0.77 | KMT2A (0.66) | TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6354131 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL9566861 | 0.76 | P4HTM (0.61) | TP53SMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |