Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357565 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL337503 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL9395526 | 0.83 | HCAR2 (0.69) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL337504 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL26288 | 0.82 | HCAR2 (0.67) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL27659194 | 0.82 | HCAR2 (0.85) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL10513327 | 0.80 | HCAR2 (0.65) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL812094 | 0.80 | HCAR2 (0.65) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL14940404 | 0.80 | HCAR2 (0.65) | HCAR2LMNAALDH1A1CA12AKR1B10 | |
| SCHEMBL9515999 | 0.80 | HCAR2 (0.65) | HCAR2LMNAALDH1A1CA12AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136721-B1 | Carboxyalkenamidocephalosporins | SHIONOGI & CO (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-4912224-A | Containing a aminothiazolyl or aminothiadiazolyl ring | SHIONOGI & CO., LTD. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4748170-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4634697-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1987-01-06 | — | — | US | disclosed |
| EP-0136721-A2 | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1985-04-10 | — | — | EP | disclosed |