Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28307095 | 0.84 | HCAR2 (0.65) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL34054 | 0.84 | HCAR2 (0.65) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL28230354 | 0.84 | HCAR2 (0.65) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL357565 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL337504 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL337503 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL9395526 | 0.83 | HCAR2 (0.69) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL11696680 | 0.82 | HCAR2 (0.62) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| Ammonia Solution, Strong SCHEMBL11584311 | 0.82 | HCAR2 (0.62) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| Ethylene SCHEMBL6402744 | 0.82 | HCAR2 (0.62) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344256-B1 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | ELIZABETH ARDEN INT SARL (CH) | 2017-04-26 | — | — | EP | claimed |
| EP-2344256-A2 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | Elizabeth Arden International, Sarl (CH) | 2011-07-20 | — | — | EP | claimed |
| WO-2010051138-A2 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | PHARMA COSMETIX RESEARCH, LLC (US) | 2010-05-06 | — | — | WO | claimed |
| US-20100086494-A1 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | PCR TECHNOLOGY HOLDINGS, LC (US) | 2010-04-08 | — | — | US | claimed |
| EP-2344256-B1 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | ELIZABETH ARDEN INT SARL (CH) | 2017-04-26 | — | — | EP | disclosed |
| US-20160151260-A1 | Skin Treatments Containing Carboxylic Acid-Substituted Idebenone Derivatives and Methods of Preparation and Use Thereof | CITIBANK, N.A., AS COLLATERAL AGENT | 2016-06-02 | — | — | US | disclosed |
| US-9290436-B2 | Compositions containing carboxylic acid-substituted derivatives | ELIZABETH ARDEN, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130101534-A1 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERlVATIVES AND METHODS OF PREPARATION AND USE THEREOF | ELIZABETH ARDEN, INC. (US) | 2013-04-25 | — | — | US | disclosed |
| US-8354550-B2 | Skin treatments containing carboxylic acid-substituted idebenone derivatives and methods of preparation and use thereof | ELIZABETH ARDEN, INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120130098-A1 | Skin Treatments Containing Carboxylic Acid-Substituted Idebenone Derivatives and Methods of Preparation and Use Thereof | ELIZABETH ARDEN, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-8173703-B2 | Skin treatments with carboxylic acid-substituted idebenone derivatives | ELIZABETH ARDEN, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| EP-2344256-A2 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | Elizabeth Arden International, Sarl (CH) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010051138-A2 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | PHARMA COSMETIX RESEARCH, LLC (US) | 2010-05-06 | — | — | WO | disclosed |
| US-20100086494-A1 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | PCR TECHNOLOGY HOLDINGS, LC (US) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130101534-A1 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERlVATIVES AND METHODS OF PREPARATION AND USE THEREOF | DECR1, ACADVL, CUTA | HCAR2 427/4885LMNA 2131/4885ALDH1A1 256/4885 |
| US-20160151260-A1 | Skin Treatments Containing Carboxylic Acid-Substituted Idebenone Derivatives and Methods of Preparation and Use Thereof | CUTA, HSD17B12, NDUFB10 | HCAR2 326/4885LMNA 1951/4885ALDH1A1 311/4885 |
| US-20100086494-A1 | SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | CUTA, HSD17B12, NDUFB10 | HCAR2 334/4885LMNA 1821/4885ALDH1A1 312/4885 |
| US-20120130098-A1 | Skin Treatments Containing Carboxylic Acid-Substituted Idebenone Derivatives and Methods of Preparation and Use Thereof | CUTA, HSD17B12, NDUFB10 | HCAR2 334/4885LMNA 1821/4885ALDH1A1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.