Butylated Hydroxytoluene

Butylated Hydroxytoluene

SCHEMBL1889653

C=CCc1ccccc1O.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
ALDH1A1 P00352 2/20 0.51
POLB P06746 2/20 0.51
TYR P14679 1/20 0.51
HSPA5 P11021 1/20 0.47
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
HIF1A Q16665 2/20 0.46
GAA P10253 2/20 0.45
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
AKR1B1 P15121 1/20 0.43
HSD17B10 Q99714 2/20 0.42
CYP2D6 P10635 1/20 0.42
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
PTGS1 P23219 2/20 0.41
PTGS2 P35354 2/20 0.41
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Allylphenol SCHEMBL9516154 0.87 CA2 (0.53) CA2ALDH1A1HSPA5GAATSHR
2-Allylphenol SCHEMBL10901820 0.86 TSHR (0.60) CA2ALDH1A1POLBHSPA5HIF1A
2-Allylphenol SCHEMBL27943724 0.85 GABRA1 (0.52) SMN1; SMN2POLBHSPA5GAAAKR1B1
SCHEMBL5462999 0.82 HSPA5 (0.66) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL1446620 0.79 CA2 (0.75) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL7590469 0.78 ALDH1A1 (0.72) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL8377430 0.78 HSPA5 (0.75) CA2SMN1; SMN2ALDH1A1POLBTYR
2-Allylphenol SCHEMBL29272030 0.78 GABRA1 (0.53) CA2ALDH1A1POLBHSPA5HIF1A
2-Allylphenol SCHEMBL27508196 0.78 GABRA1 (0.53) CA2ALDH1A1POLBHSPA5HIF1A
2-Allylphenol SCHEMBL29039614 0.78 GABRA1 (0.37) SMN1; SMN2ALDH1A1POLBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935322-B2 Solvent extraction process for separating cobalt and/or nickel from impurities in leach solutions Commonwealth Scientific & Indistrial Research Organisation (AU) 2011-05-03 US disclosed
US-20080038168-A1 Solvent Extraction Process For Separating Cobalt And/Or Manganese From Impurities In Leach Solutions COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-02-14 US disclosed
US-20070248514-A1 Solvent Extraction Process for Separating Cobalt and/or Nickel from Impurities in Leach Solutions COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 2007-10-25 US disclosed