Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | BHMT | Q93088 | 2/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901839 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL18470038 | 0.88 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL15948624 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL1106823 | 0.81 | CYP2D6 (0.46) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL8613878 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL12132165 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL10697807 | 0.81 | BHMT (0.51) | ALDH1A1HPGDHSD17B10LMNAKMT2A | |
| SCHEMBL7134945 | 0.79 | — | — | |
| SCHEMBL18534154 | 0.79 | — | — | |
| SCHEMBL24218762 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345847-B1 | PROCESS FOR THE PREPARATION OF POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| EP-0345847-A1 | Process for the preparation of polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-13 | — | — | EP | disclosed |