Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536792 | 0.81 | LMNA (0.74) | BHMTTSHRLMNATDP1KMT2A | |
| SCHEMBL9516370 | 0.81 | ALDH1A1 (0.52) | BHMTTSHRLMNATDP1KMT2A | |
| SCHEMBL812501 | 0.81 | ALDH1A1 (0.61) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL2280524 | 0.81 | LMNA (0.65) | BHMTTSHRLMNATDP1KMT2A | |
| SCHEMBL21703159 | 0.79 | TSHR (0.60) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL4815884 | 0.79 | TSHR (0.60) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL20993533 | 0.79 | TSHR (0.60) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL5168783 | 0.79 | TSHR (0.67) | BHMTTSHRLMNATDP1KMT2A | |
| SCHEMBL20475058 | 0.79 | TSHR (0.67) | BHMTTSHRLMNATDP1KMT2A | |
| SCHEMBL7693275 | 0.79 | TSHR (0.67) | BHMTTSHRLMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271287-A2 | Quinoline dioic acids and amides | MERCK FROSST CANADA INC. (CA) | 1988-06-15 | — | — | EP | disclosed |