SCHEMBL951656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14370444	0.97	CYP17A1 (0.41)	CYP17A1CYP19A1
	SCHEMBL212781	0.88	CYP17A1 (0.41)	CYP17A1CYP19A1EPHX2
	SCHEMBL951658	0.86	CYP17A1 (0.38)	CYP17A1CYP19A1
	SCHEMBL214191	0.85	CYP17A1 (0.42)	CYP17A1CYP19A1
	SCHEMBL13922296	0.83	CYP17A1 (0.39)	CYP17A1CYP19A1
	SCHEMBL14370445	0.82	—	—
	SCHEMBL12914637	0.81	CYP17A1 (0.44)	CYP17A1CYP19A1EPHX2
	SCHEMBL14523962	0.81	CYP17A1 (0.39)	CYP17A1CYP19A1
	SCHEMBL854489	0.80	CYP17A1 (0.45)	CYP17A1CYP19A1EPHX2
	SCHEMBL210246	0.80	CYP19A1 (0.45)	CYP17A1CYP19A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.