Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518458 | 0.90 | HTT (0.57) | TSHRHTTHDAC3HDAC4HDAC1 | |
| SCHEMBL6903284 | 0.89 | TSHR (0.58) | TSHRHTTHCRTR1KDM4EALDH1A1 | |
| SCHEMBL8652703 | 0.84 | TSHR (0.53) | TSHRHTTHCRTR1KDM4EALDH1A1 | |
| SCHEMBL30508514 | 0.84 | KMT2A (0.61) | TSHRHTTHDAC3HDAC4HDAC1 | |
| SCHEMBL7150327 | 0.84 | KMT2A (0.61) | TSHRHTTHDAC3HDAC4HDAC1 | |
| SCHEMBL9570919 | 0.84 | ALDH1A1 (0.54) | TSHRHTTHCRTR1KDM4EALDH1A1 | |
| SCHEMBL1063005 | 0.82 | TSHR (0.66) | TSHRHTTHCRTR1KDM4EALDH1A1 | |
| SCHEMBL2080518 | 0.82 | TSHR (0.51) | TSHRHTTHCRTR1KDM4EALDH1A1 | |
| SCHEMBL12308186 | 0.81 | HTT (0.58) | TSHRHTTHDAC3HDAC4HDAC1 | |
| SCHEMBL7255678 | 0.81 | HTT (0.62) | TSHRHTTHCRTR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465342-B1 | REDUCING COSMETIC COMPOSITION FOR PERMING CONTAINING A DERIVATIVE OF A N-(MERCAPTO-ALKYL)SUCCINAMIC ACID OR A N-(MERCAPTO-ALKYL)SUCCINIMID AND ITS USE IN A PROCESS FOR PERMANENT HAIR SHAPING | L'OREAL (FR) | 1993-09-29 | — | — | EP | claimed |