Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516588 | 0.90 | TSHR (0.51) | HTTTSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL6903284 | 0.86 | TSHR (0.58) | HTTTSHRHPGDNPC1ALDH1A1 | |
| SCHEMBL9518417 | 0.85 | HTT (0.59) | HTTTSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL7255678 | 0.85 | HTT (0.62) | HTTTSHRHPGDALOX5NAAA | |
| SCHEMBL308733 | 0.83 | HTT (0.57) | HTTTSHRHPGDALOX5NAAA | |
| SCHEMBL30415135 | 0.83 | HTT (0.57) | HTTTSHRHPGDALOX5NAAA | |
| SCHEMBL5702819 | 0.83 | TSHR (0.83) | HTTTSHRHPGDNAAAALDH1A1 | |
| SCHEMBL8620126 | 0.83 | ALDH1A1 (0.57) | HTTTSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL8654054 | 0.83 | HTT (0.57) | HTTTSHRHDAC3HDAC1HPGD | |
| SCHEMBL8653159 | 0.82 | TSHR (0.56) | HTTTSHRHDAC3HDAC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465342-B1 | REDUCING COSMETIC COMPOSITION FOR PERMING CONTAINING A DERIVATIVE OF A N-(MERCAPTO-ALKYL)SUCCINAMIC ACID OR A N-(MERCAPTO-ALKYL)SUCCINIMID AND ITS USE IN A PROCESS FOR PERMANENT HAIR SHAPING | L'OREAL (FR) | 1993-09-29 | — | — | EP | claimed |