Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907136 | 0.86 | MEN1 (0.43) | ALDH1A1CYP3A4TSHRPGRGAA | |
| SCHEMBL17863579 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CYP1A2LMNAHSD17B10 | |
| SCHEMBL27937248 | 0.79 | CYP1A2 (0.52) | ALDH1A1CYP3A4CYP1A2TSHRCYP19A1 | |
| SCHEMBL20879477 | 0.76 | TDP1 (0.41) | ALDH1A1CYP3A4HSD17B10POLBTSHR | |
| SCHEMBL677823 | 0.76 | CA12 (0.44) | ALDH1A1CYP3A4CYP1A2MAPTLMNA | |
| SCHEMBL11393581 | 0.74 | POLB (0.31) | NPC1RAB9AMAPTPOLB | |
| SCHEMBL4186797 | 0.73 | UGT2B7 (0.52) | ALDH1A1CYP3A4CYP1A2MAPTTSHR | |
| SCHEMBL9226980 | 0.73 | ALDH1A1 (0.51) | ALDH1A1CYP3A4RAB9ALMNATSHR | |
| SCHEMBL28569670 | 0.73 | POLB (0.38) | ALDH1A1CYP3A4CYP1A2MAPTLMNA | |
| SCHEMBL27918628 | 0.73 | ACHE (0.51) | CYP3A4CYP1A2LMNATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |