Phosphoric Acid

SCHEMBL9516746

CC(C)(C)c1ccc(O)c(C(C)(C)C)c1Cc1c(C(C)(C)C)ccc(O)c1C(C)(C)C.CC(C)(C)c1ccc(O)c(C(C)(C)C)c1Cc1c(C(C)(C)C)ccc(O)c1C(C)(C)C.CC(C)(C)c1ccc(O)c(C(C)(C)C)c1Cc1c(C(C)(C)C)ccc(O)c1C(C)(C)C.O=P([O-])([O-])[O-].[Na+].[Na+].[Na+]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	HSP90AA1	P07900	1/20	0.35

▸	HSP90AB1	P08238	1/20	0.35

▸	ALDH1A1	P00352	4/20	0.34

▸	CYP2C9	P11712	2/20	0.34

▸	ALOX15	P16050	2/20	0.34

▸	NR1I2	O75469	2/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	MIF	P14174	1/20	0.34

▸	TYR	P14679	1/20	0.34

▸	HTT	P42858	1/20	0.34

▸	NFE2L2	Q16236	1/20	0.34

▸	HSD17B10	Q99714	1/20	0.34

▸	TSHR	P16473	1/20	0.32

▸	TDP1	Q9NUW8	1/20	0.32

▸	SMN1; SMN2	Q16637	2/20	0.32

▸	TP53	P04637	1/20	0.32

▸	CYP2C19	P33261	1/20	0.32

▸	HIF1A	Q16665	1/20	0.32

▸	KDM4E	B2RXH2	1/20	0.31

▸	CYP1A2	P05177	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL5557414	1.00	HSP90AA1 (0.35)	HSP90AA1HSP90AB1ALDH1A1CYP2C9ALOX15
Phosphoric Acid SCHEMBL5080253	0.90	HSP90AA1 (0.36)	HSP90AA1HSP90AB1ALDH1A1CYP2C9ALOX15
SCHEMBL7625000	0.88	ALDH1A1 (0.42)	HSP90AA1HSP90AB1ALDH1A1CYP2C9ALOX15
SCHEMBL29406783	0.88	ALDH1A1 (0.42)	HSP90AA1HSP90AB1ALDH1A1CYP2C9ALOX15
SCHEMBL5179960	0.87	HSP90AA1 (0.30)	HSP90AA1HSP90AB1
SCHEMBL30951029	0.87	HSP90AA1 (0.30)	HSP90AA1HSP90AB1
SCHEMBL29391738	0.86	ALDH1A1 (0.41)	HSP90AA1HSP90AB1ALDH1A1CYP2C9ALOX15
SCHEMBL5080249	0.80	INPPL1 (0.37)	HSP90AA1HSP90AB1
SCHEMBL5557410	0.79	INPPL1 (0.36)	HSP90AA1HSP90AB1
SCHEMBL29656761	0.77	ALDH1A1 (0.42)	HSP90AA1HSP90AB1ALDH1A1CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0278409-B1	GLASS FIBER REINFORCED POLYOLEFIN RESIN COMPOSITION	IDEMITSU PETROCHEMICAL CO. LTD. (JP)	1993-09-15	—	—	EP	claimed