Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517223 | 0.93 | P4HTM (0.41) | P4HTML3MBTL1TSHRGSK3BGABRA5 | |
| SCHEMBL9515950 | 0.86 | GABRA5 (0.40) | P4HTML3MBTL1GABRA5MEN1NPC1 | |
| SCHEMBL9516030 | 0.85 | GABRA5 (0.44) | P4HTML3MBTL1GABRA5MEN1NPC1 | |
| SCHEMBL9516040 | 0.84 | GABRA5 (0.41) | P4HTML3MBTL1TSHRGSK3BGABRA5 | |
| SCHEMBL9516300 | 0.83 | GABRA5 (0.48) | P4HTML3MBTL1GABRA5ALDH1A1HDAC6 | |
| SCHEMBL9516953 | 0.81 | P4HTM (0.39) | P4HTML3MBTL1TSHRGSK3BGABRA5 | |
| SCHEMBL9518142 | 0.81 | P4HTM (0.47) | P4HTML3MBTL1GABRA5MEN1NPC1 | |
| SCHEMBL9517187 | 0.80 | NPC1 (0.40) | P4HTML3MBTL1GABRA5HDAC6MEN1 | |
| SCHEMBL9516209 | 0.80 | P4HTM (0.38) | P4HTML3MBTL1TSHRGSK3BGABRA5 | |
| SCHEMBL9517984 | 0.80 | GABRA5 (0.42) | P4HTML3MBTL1GABRA5MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |