Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516040 | 0.95 | GABRA5 (0.41) | P4HTMGABRA5GSK3BHDAC6L3MBTL1 | |
| SCHEMBL9517019 | 0.90 | GABRA5 (0.40) | P4HTMGABRA5HDAC6SCN9ASCN5A | |
| SCHEMBL9516953 | 0.88 | P4HTM (0.39) | P4HTMGABRA5GSK3BHDAC6L3MBTL1 | |
| SCHEMBL9517223 | 0.86 | P4HTM (0.41) | P4HTMGABRA5GSK3BHDAC6L3MBTL1 | |
| SCHEMBL9517918 | 0.85 | GABRA5 (0.43) | P4HTMGABRA5TSHRSCN9ASCN5A | |
| SCHEMBL9516888 | 0.84 | GABRA5 (0.50) | P4HTMGABRA5HDAC6SCN9AALDH1A1 | |
| SCHEMBL9517043 | 0.83 | P4HTM (0.40) | P4HTMGABRA5GSK3BHDAC6L3MBTL1 | |
| SCHEMBL9519639 | 0.83 | P4HTM (0.47) | P4HTMGABRA5HDAC6L3MBTL1SCN9A | |
| SCHEMBL9516194 | 0.82 | GABRA5 (0.38) | P4HTMGABRA5HDAC6L3MBTL1TSHR | |
| SCHEMBL9517010 | 0.81 | P4HTM (0.47) | P4HTMGABRA5HDAC6SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |