Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517004 | 0.85 | TP53 (0.57) | SLC22A12ALOX12SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9517896 | 0.83 | AR (0.46) | SLC22A12LMNAHTTCYP1A2CYP3A4 | |
| SCHEMBL9517269 | 0.83 | SLC22A12 (0.60) | SLC22A12ALOX12HTTCYP2D6CYP2C9 | |
| SCHEMBL9519315 | 0.81 | KEAP1 (0.63) | LMNAALOX12HTTTSHRSMN1; SMN2 | |
| SCHEMBL9519540 | 0.80 | MEN1 (0.63) | SLC22A12LMNAALOX12HTTCYP3A4 | |
| SCHEMBL13898348 | 0.79 | AR (0.64) | LMNAHTTSMN1; SMN2ARMAPT | |
| SCHEMBL8869556 | 0.78 | POLB (0.45) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8869973 | 0.78 | CYP1A2 (0.46) | LMNAHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8867662 | 0.78 | SCN9A (0.48) | LMNAHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8868611 | 0.77 | EGLN1 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |