Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519180 | 0.87 | HDAC1 (0.52) | MAPTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9517953 | 0.85 | TRPV1 (0.51) | ARLMNACACNA1HCACNA1BKMT2A | |
| SCHEMBL9517066 | 0.83 | SLC22A12 (0.54) | ARLMNACACNA1HCACNA1BKMT2A | |
| SCHEMBL9518021 | 0.83 | LMNA (0.56) | LMNAMAPTMAPK1SMN1; SMN2HTT | |
| SCHEMBL9422522 | 0.82 | MEN1 (0.55) | ARLMNAKMT2AMEN1MAPT | |
| SCHEMBL9515597 | 0.81 | P4HTM (0.48) | KMT2AMEN1CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL8869973 | 0.80 | CYP1A2 (0.46) | ARLMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL9517930 | 0.79 | PSEN1 (0.54) | ARKMT2ACYP2C9CYP3A4CYP2D6 | |
| SCHEMBL8868341 | 0.79 | CYP1A2 (0.45) | ARLMNACACNA1HCACNA1BKMT2A | |
| SCHEMBL9519183 | 0.78 | CES1 (0.58) | ARKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |