Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517066 | 0.85 | SLC22A12 (0.54) | SLC22A12SMN1; SMN2ALDH1A1MAPK1MEN1 | |
| SCHEMBL9519315 | 0.83 | KEAP1 (0.63) | FFAR4SMN1; SMN2ALDH1A1MAPK1MEN1 | |
| SCHEMBL9517269 | 0.82 | SLC22A12 (0.60) | FFAR4SLC22A12HDAC1HDAC8HDAC3 | |
| SCHEMBL6756075 | 0.82 | FFAR4 (0.68) | TP53FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL14601690 | 0.82 | FFAR4 (0.68) | TP53FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL9519540 | 0.82 | MEN1 (0.63) | FFAR4SLC22A12SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9519180 | 0.81 | HDAC1 (0.52) | TP53FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL7570513 | 0.80 | FFAR4 (0.64) | TP53FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL26530291 | 0.79 | GAA (0.68) | TP53FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL95648 | 0.79 | FFAR4 (0.60) | TP53FFAR4HDAC1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |