Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519540 | 0.84 | MEN1 (0.63) | KMT2ASLC22A12LMNASMN1; SMN2MEN1 | |
| SCHEMBL9517099 | 0.83 | TSHR (0.69) | PGRKMT2ASLC22A12LMNAHDAC1 | |
| SCHEMBL13807498 | 0.81 | PGR (0.68) | PGRKMT2ALMNASMN1; SMN2HDAC3 | |
| SCHEMBL23565665 | 0.80 | KMT2A (0.71) | PGRKMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL95797 | 0.78 | PGR (0.65) | PGRKMT2ALMNASMN1; SMN2HDAC3 | |
| SCHEMBL17858628 | 0.78 | SLC22A12 (0.54) | PGRKMT2ASLC22A12KITLMNA | |
| SCHEMBL13248875 | 0.77 | KIT (0.46) | PGRKMT2AKITLMNASMN1; SMN2 | |
| SCHEMBL1095392 | 0.75 | SLC22A12 (0.60) | SLC22A12 | |
| SCHEMBL19995039 | 0.75 | KMT2A (0.55) | PGRKMT2AKITLMNASMN1; SMN2 | |
| SCHEMBL9516051 | 0.75 | PSEN1 (0.64) | KMT2ASLC22A12KITLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |