Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517399 | 1.00 | MAOB (0.46) | MAOBCALM1TSHRALDH1A1IDO1 | |
| SCHEMBL9517397 | 1.00 | MAOB (0.46) | MAOBCALM1TSHRALDH1A1IDO1 | |
| SCHEMBL29702980 | 0.75 | CALM1 (0.50) | MAOBCALM1TSHRALDH1A1IDO1 | |
| SCHEMBL9400817 | 0.75 | ALDH1A1 (0.50) | MAOBCALM1TSHRALDH1A1IDO1 | |
| Bromide SCHEMBL11513184 | 0.73 | ALDH1A1 (0.48) | MAOBCALM1TSHRALDH1A1IDO1 | |
| Iodide SCHEMBL11594153 | 0.73 | ALDH1A1 (0.48) | MAOBCALM1TSHRALDH1A1IDO1 | |
| SCHEMBL465742 | 0.71 | — | — | |
| SCHEMBL465636 | 0.67 | TP53 (0.50) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| SCHEMBL218806 | 0.65 | — | — | |
| SCHEMBL62125 | 0.63 | ALDH1A1 (0.69) | MAOBCALM1ALDH1A1LOXL2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345847-B1 | PROCESS FOR THE PREPARATION OF POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| EP-0345847-A1 | Process for the preparation of polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-13 | — | — | EP | disclosed |