Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SCN4A | P35499 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495276 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL31219323 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL14726160 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL5028769 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL9518625 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL8652406 | 0.73 | RAB9A (0.78) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL20856609 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL22130237 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL11816243 | 0.72 | APP (0.58) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL9848729 | 0.71 | NPC1 (0.66) | SMN1; SMN2MAPTNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374040-B1 | 2-IMINO-BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1993-03-24 | — | — | EP | disclosed |
| EP-0374040-A1 | 2-Imino-benzothiazoline derivatives, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-06-20 | — | — | EP | disclosed |