Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856609 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL5448236 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL19132858 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL9517440 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL9717710 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL334946 | 0.72 | RAB9A (0.66) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL7495276 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL30500275 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3851081 | 0.71 | RAB9A (0.63) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL2055263 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374040-B1 | 2-IMINO-BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1993-03-24 | — | — | EP | disclosed |
| EP-0374040-A1 | 2-Imino-benzothiazoline derivatives, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-06-20 | — | — | EP | disclosed |