Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14310499 | 0.87 | KCNQ3 (0.46) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL9517489 | 0.85 | CES2 (0.57) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL3179802 | 0.78 | CES2 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL27561994 | 0.78 | SRD5A2 (0.53) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL479072 | 0.76 | TSHR (0.65) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL3026551 | 0.76 | KCNQ3 (0.51) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| Hydrochloric Acid SCHEMBL31439010 | 0.75 | TSHR (0.63) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL1719358 | 0.75 | KCNQ3 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL31163926 | 0.75 | KCNQ3 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL29499491 | 0.75 | KCNQ3 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411252-B1 | Process for the preparation of fluorobenzoic acids | RIEDEL DE HAEN AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-5093529-A | Process for the preparation of fluorinated benzoic acids | CASSELLA AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0411252-A1 | Process for the preparation of fluorobenzoic acids | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1991-02-06 | — | — | EP | disclosed |