Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900022 | 0.93 | MAOB (0.43) | MAOBMAOASLC6A4SLC6A3GRIN1 | |
| SCHEMBL11247712 | 0.84 | MAOB (0.37) | MAOBMAOASLC6A4SLC6A3GRIN1 | |
| SCHEMBL28611458 | 0.82 | CHRNA1 (0.41) | MAOBMAOASLC6A4SLC6A3GRIN1 | |
| SCHEMBL11239617 | 0.81 | SLC6A4 (0.37) | MAOBMAOASLC6A4SLC6A3GRIN1 | |
| SCHEMBL10363964 | 0.81 | LTA4H (0.38) | MAOA | |
| SCHEMBL28614545 | 0.81 | MAOB (0.42) | MAOBMAOASLC6A4SLC6A3CYP3A4 | |
| SCHEMBL10848899 | 0.80 | MAOB (0.41) | MAOBMAOASLC6A4SLC6A3GRIN1 | |
| SCHEMBL11250705 | 0.78 | MAOB (0.39) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL28599789 | 0.77 | SLC6A4 (0.37) | MAOBMAOASLC6A4SLC6A3CYP3A4 | |
| SCHEMBL2082060 | 0.77 | CA12 (0.41) | MAOBMAOASLC6A4SLC6A3GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034871-B2 | PROCESS FOR PREPARING ESTERS OF ALKANOIC ACIDS VIA REARRANGEMENT OF ALPHA-HALOKETALS | BLASCHIM S.p.A. (IT) | 1993-08-25 | — | — | EP | disclosed |
| US-4748253-A | Process for preparing esters of alkanoic acids via rearrangement of alpha-haloketals | BLASINACHIM S.P.A. (IT) | 1988-05-31 | — | — | US | disclosed |
| EP-0034871-B1 | PROCESS FOR PREPARING ESTERS OF ALKANOIC ACIDS VIA REARRANGEMENT OF ALPHA-HALOKETALS | BLASCHIM S.p.A. (IT) | 1985-07-31 | — | — | EP | disclosed |
| EP-0034871-A2 | Process for preparing esters of alkanoic acids via rearrangement of alpha-haloketals | BLASCHIM S.p.A. (IT) | 1981-09-02 | — | — | EP | disclosed |