Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765076 | 0.87 | L3MBTL1 (0.79) | CA2CA9HDAC3HDAC1HDAC2 | |
| SCHEMBL166980 | 0.86 | L3MBTL1 (0.71) | CA2CA9HDAC3HDAC1HDAC2 | |
| SCHEMBL2186352 | 0.85 | HDAC2 (0.72) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17117429 | 0.85 | HPGD (0.84) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL6400294 | 0.84 | LMNA (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4074353 | 0.84 | HDAC3 (0.87) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7440269 | 0.83 | LMNA (0.82) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7280705 | 0.83 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL3825861 | 0.82 | HDAC3 (0.68) | CA2CA9HDAC3HDAC1HDAC2 | |
| SCHEMBL9517546 | 0.82 | GAA (0.70) | HPGDALDH1A1SMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5151447-A | Bactericides and fungicides | ROHM AND HAAS COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5023275-A | S-substituted beta-thioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |