Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.62 |
| ▸ | PNP | P00491 | 6/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TK1 | P04183 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273799 | 0.92 | HPRT1 (0.64) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL1665922 | 0.87 | PNP (0.58) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL1663883 | 0.87 | PNP (0.58) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL10496683 | 0.86 | PNP (0.62) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL10506595 | 0.84 | TK1 (0.65) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL16491196 | 0.83 | BLM (0.61) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL16197453 | 0.83 | PNP (0.58) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL16039082 | 0.83 | PNP (0.58) | HPRT1PNPBLMUSP2TSHR | |
| Omaciclovir SCHEMBL417577 | 0.81 | TK1 (0.62) | HPRT1PNPBLMUSP2TSHR | |
| Omaciclovir SCHEMBL712427 | 0.81 | TK1 (0.62) | HPRT1PNPBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216141-A | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES | BENNER, STEVEN | 1993-06-01 | — | — | US | disclosed |
| EP-0418309-A4 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0418309-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER, Steven Albert (CH) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989012060-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER STEVEN ALBERT (CH) | 1989-12-14 | — | — | WO | disclosed |