Methacrylic Acid

Methacrylic Acid

SCHEMBL9517609

C=C(C)C(=O)O.C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)C=C

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.58
ALDH1A1 P00352 5/20 0.55
HIF1A Q16665 4/20 0.55
TP53 P04637 3/20 0.55
CYP3A4 P08684 2/20 0.55
MAPK1 P28482 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TSHR P16473 7/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL7196280 1.00 THRB (0.58) THRBALDH1A1HIF1ATP53CYP3A4
SCHEMBL18258532 0.91 THRB (0.60) THRBALDH1A1HIF1ATP53CYP3A4
Methacrylic Acid SCHEMBL15789442 0.91 ALDH1A1 (0.62) THRBALDH1A1HIF1ATP53CYP3A4
SCHEMBL238953 0.89 THRB (0.70) THRBALDH1A1HIF1ATP53CYP3A4
SCHEMBL64779 0.88 THRB (0.57) THRBALDH1A1HIF1ATP53CYP3A4
SCHEMBL6473695 0.88 THRB (0.57) THRBALDH1A1HIF1ATP53CYP3A4
SCHEMBL25989985 0.88 THRB (0.60) THRBALDH1A1HIF1ATP53CYP3A4
Acrylic Acid SCHEMBL18580288 0.87 THRB (0.64) THRBALDH1A1HIF1ATP53CYP3A4
Acrylic Acid SCHEMBL17101615 0.87 THRB (0.64) THRBALDH1A1HIF1ATP53CYP3A4
SCHEMBL17947498 0.86 THRB (0.62) THRBALDH1A1HIF1ATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021027210-A1 LUBRICATING OIL VISCOSITY INDEX MODIFYING AGENT CONTAINING STAR-SHAPED SEP COPOLYMER AND PREPARATION METHOD THEREFOR 深圳昆油石化技术有限公司 2021-02-18 WO claimed
EP-0220862-B1 REACTIVE, ACRYLIC RESIN MICRO-PARTICLES, ITS PREPARATION AND CURABLE COMPOSITION CONTAINING THE SAME Nippon Paint Co., Ltd. (JP) 1993-08-25 EP disclosed