Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517661 | 0.90 | GRM4 (0.43) | GRM4TAAR1PSEN1PSEN2APH1B | |
| SCHEMBL9518382 | 0.85 | TAAR1 (0.55) | TAAR1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL4598382 | 0.81 | GRM4 (0.44) | GRM4TAAR1PSEN1PSEN2APH1B | |
| SCHEMBL4598374 | 0.81 | GRM4 (0.44) | GRM4TAAR1PSEN1PSEN2APH1B | |
| SCHEMBL4824953 | 0.81 | GRM4 (0.44) | GRM4TAAR1PSEN1PSEN2APH1B | |
| SCHEMBL15791011 | 0.79 | TAAR1 (0.52) | TAAR1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL16141270 | 0.79 | TAAR1 (0.52) | TAAR1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL4819619 | 0.79 | L3MBTL1 (0.47) | GRM4TAAR1PSEN1PSEN2APH1B | |
| SCHEMBL17983408 | 0.76 | EPHX1 (0.40) | GRM4TAAR1PSEN1PSEN2APH1B | |
| SCHEMBL19884369 | 0.75 | NAAA (0.44) | GRM4TAAR1EPHX1NAAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465342-B1 | REDUCING COSMETIC COMPOSITION FOR PERMING CONTAINING A DERIVATIVE OF A N-(MERCAPTO-ALKYL)SUCCINAMIC ACID OR A N-(MERCAPTO-ALKYL)SUCCINIMID AND ITS USE IN A PROCESS FOR PERMANENT HAIR SHAPING | L'OREAL (FR) | 1993-09-29 | — | — | EP | claimed |