Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10896768 | 0.84 | MAPT (0.45) | MAPTPKMGLALMNAKMT2A | |
| SCHEMBL112161 | 0.81 | KAT2B (0.70) | KAT2BMAPTPKMLMNAKMT2A | |
| SCHEMBL29519350 | 0.81 | KAT2B (0.70) | KAT2BMAPTPKMLMNAKMT2A | |
| SCHEMBL8655505 | 0.80 | KAT2B (0.56) | KAT2BMAPTLMNAKMT2ARAB9A | |
| SCHEMBL1889528 | 0.80 | PKM (0.45) | MAPTPKMGLAKMT2ARAB9A | |
| SCHEMBL1741987 | 0.80 | ALDH1A1 (0.54) | MAPTPKMLMNAKMT2ATDP1 | |
| SCHEMBL7182851 | 0.80 | KAT2B (0.54) | KAT2BMAPTPKMLMNAKMT2A | |
| SCHEMBL6218547 | 0.79 | KAT2B (0.74) | KAT2BMAPTPKMLMNAKMT2A | |
| SCHEMBL2080430 | 0.78 | KAT2B (0.65) | KAT2BMAPTPKMLMNAKMT2A | |
| SCHEMBL7719476 | 0.78 | TDP1 (0.42) | KAT2BMAPTPKMGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391662-B1 | Nitroaniline dyes with a cyano substituent group | BRISTOL MYERS SQUIBB CO (US) | 1993-10-27 | — | — | EP | claimed |
| US-5024673-A | Colorfast direct yellow hair dye | CLAIROL INCORPORATED (US) | 1991-06-18 | — | — | US | claimed |
| US-4980158-A | HAIR DYES; PHOTOSTABILITY, WASHFASTNESS | CLAIROL INCORPORATED (US) | 1990-12-25 | — | — | US | claimed |
| EP-0391662-A1 | Nitroaniline dyes with a cyano substituent group | Bristol-Myers Squibb Company (US) | 1990-10-10 | — | — | EP | claimed |
| EP-0391662-B1 | Nitroaniline dyes with a cyano substituent group | BRISTOL MYERS SQUIBB CO (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5024673-A | Colorfast direct yellow hair dye | CLAIROL INCORPORATED (US) | 1991-06-18 | — | — | US | disclosed |
| US-4980158-A | HAIR DYES; PHOTOSTABILITY, WASHFASTNESS | CLAIROL INCORPORATED (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0391662-A1 | Nitroaniline dyes with a cyano substituent group | Bristol-Myers Squibb Company (US) | 1990-10-10 | — | — | EP | disclosed |