Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933940 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9514367 | 0.79 | GAA (0.44) | NPSR1 | |
| SCHEMBL7666433 | 0.76 | NCEH1 (0.43) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8035953 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4E | |
| SCHEMBL13133119 | 0.73 | MAPK1 (0.51) | L3MBTL1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL9514788 | 0.73 | PTPN1 (0.43) | L3MBTL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL15288342 | 0.73 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9516688 | 0.72 | CNR2 (0.41) | ALDH1A1MAPTSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL5254664 | 0.72 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1MAPTMEN1MAPK1 | |
| SCHEMBL9516695 | 0.72 | PTGS1 (0.49) | L3MBTL1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511228-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-04 | — | — | EP | claimed |
| WO-1991010430-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-07-25 | — | — | WO | claimed |
| US-5006555-A | Antiinflammatory, antithrombin, respiratory system disorder treatment | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-09 | — | — | US | claimed |
| EP-0511228-A4 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0511228-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-04 | — | — | EP | disclosed |
| WO-1991010430-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |
| US-5006555-A | Antiinflammatory, antithrombin, respiratory system disorder treatment | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-09 | — | — | US | disclosed |