Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516695 | 0.80 | PTGS1 (0.49) | L3MBTL1MEN1KMT2A | |
| SCHEMBL9514367 | 0.77 | GAA (0.44) | — | |
| SCHEMBL29357471 | 0.76 | MAPT (0.53) | L3MBTL1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL455028 | 0.76 | MAPT (0.53) | L3MBTL1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL6933940 | 0.76 | SMN1; SMN2 (0.47) | BACE1KDM4ENPC1RAB9A | |
| SCHEMBL7666433 | 0.74 | NCEH1 (0.43) | PTPN1BACE1KDM4ENPC1RAB9A | |
| SCHEMBL9517997 | 0.73 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8035953 | 0.72 | ALDH1A1 (0.45) | BACE1KDM4E | |
| SCHEMBL20414574 | 0.71 | NCEH1 (0.51) | MEN1KMT2ACETP | |
| SCHEMBL10895815 | 0.71 | HTT (0.49) | L3MBTL1TDP1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511228-A4 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | — | 1993-04-21 | — | — | EP | claimed |
| EP-0511228-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-04 | — | — | EP | claimed |
| WO-1991010430-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-07-25 | — | — | WO | claimed |
| US-5006555-A | Antiinflammatory, antithrombin, respiratory system disorder treatment | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-09 | — | — | US | claimed |
| EP-0511228-A4 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0511228-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-04 | — | — | EP | disclosed |
| WO-1991010430-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |
| US-5006555-A | Antiinflammatory, antithrombin, respiratory system disorder treatment | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-09 | — | — | US | disclosed |