Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516250 | 0.89 | CA2 (0.46) | SMN1; SMN2KMT2AP4HTMKDM4EALDH1A1 | |
| SCHEMBL9516171 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2FBP1CASP3KMT2AP4HTM | |
| SCHEMBL9141271 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2FBP1KMT2ABCL2L1MCL1 | |
| SCHEMBL9138978 | 0.83 | P4HTM (0.61) | SMN1; SMN2FBP1CASP3KMT2ABCL2L1 | |
| SCHEMBL9517068 | 0.82 | CASP3 (0.47) | SMN1; SMN2CASP3KMT2AP4HTMMEN1 | |
| SCHEMBL8868877 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2FBP1KMT2ABCL2L1MCL1 | |
| SCHEMBL9515532 | 0.82 | P4HTM (0.61) | CASP3BCL2L1MCL1P4HTMKAT6A | |
| SCHEMBL9018092 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2FBP1CASP3KMT2ABCL2L1 | |
| SCHEMBL8868132 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2FBP1KMT2ABCL2L1MCL1 | |
| SCHEMBL9142109 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2FBP1CASP3KMT2ABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |