Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.67 |
| ▸ | DRD3 | P35462 | 4/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484811 | 0.90 | BCHE (0.62) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL11653358 | 0.90 | DRD2 (0.64) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL18114865 | 0.88 | OPRK1 (0.74) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL18114903 | 0.87 | OPRK1 (0.74) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL18114873 | 0.85 | DRD2 (0.64) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL11655881 | 0.85 | AOC3 (0.64) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL18114801 | 0.84 | OPRK1 (0.73) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL8593830 | 0.84 | TAAR1 (0.57) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL4448222 | 0.82 | OPRM1 (0.74) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL3854492 | 0.82 | OPRM1 (0.74) | DRD2OPRM1DRD3OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395529-B1 | Hydroxyphenethylamine derivative and its salts, method of preparation, medical application and use as specific pharmacological tool | ROUSSEL UCLAF (FR) | 1993-11-03 | — | — | EP | disclosed |
| US-5141962-A | N-pentyl-n-phenethyl-3-hydroxyphenethylamine as antagonist for opiate receptor | ROUSSEL UCLAF (FR) | 1992-08-25 | — | — | US | disclosed |
| EP-0395529-A1 | Hydroxyphenethylamine derivative and its salts, method of preparation, medical application and use as specific pharmacological tool | ROUSSEL-UCLAF (FR) | 1990-10-31 | — | — | EP | disclosed |