Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3745991 | 0.82 | TAAR1 (0.47) | L3MBTL1LTB4RCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9518299 | 0.76 | PDE10A (0.32) | SLC5A2 | |
| SCHEMBL9518287 | 0.72 | RXFP1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL10539073 | 0.71 | RXFP1 (0.33) | — | |
| SCHEMBL10843817 | 0.70 | SLC5A2 (0.43) | SLC5A2KCNH2HRH3P2RX3CYP2D6 | |
| SCHEMBL31023943 | 0.70 | SLC5A2 (0.46) | SLC5A2KCNH2HRH3CYP2D6SLC6A4 | |
| SCHEMBL10845738 | 0.70 | SLC5A2 (0.46) | SLC5A2KCNH2HRH3CYP2D6SLC6A4 | |
| SCHEMBL12188952 | 0.70 | PARP1 (0.44) | SLC5A2KCNH2HRH3P2RX3CYP2D6 | |
| SCHEMBL9518879 | 0.70 | RXFP1 (0.35) | CYP2D6 | |
| SCHEMBL18648047 | 0.70 | TAAR1 (0.47) | SLC5A2CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |