Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10539073 | 0.99 | RXFP1 (0.33) | RXFP1HTTRAB9ASMN1; SMN2USP2 | |
| SCHEMBL2101659 | 0.82 | KCNH2 (0.39) | — | |
| SCHEMBL9518879 | 0.79 | RXFP1 (0.35) | RXFP1HTTRAB9ASMN1; SMN2USP2 | |
| Hydrochloric Acid SCHEMBL10538266 | 0.78 | RXFP1 (0.34) | RXFP1HTTRAB9ASMN1; SMN2USP2 | |
| SCHEMBL9518430 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL9518271 | 0.72 | SLC5A2 (0.39) | — | |
| SCHEMBL9518260 | 0.71 | — | — | |
| SCHEMBL34464549 | 0.70 | GRM5 (0.34) | RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL12824889 | 0.70 | ALDH1A1 (0.39) | RXFP1HTTRAB9ASMN1; SMN2USP2 | |
| SCHEMBL34464514 | 0.69 | ADRA2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | claimed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | claimed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | claimed |
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |