Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518271 | 0.76 | SLC5A2 (0.39) | SLC5A2 | |
| SCHEMBL23612453 | 0.74 | PARP1 (0.42) | PDE10ASLC5A1SLC5A2 | |
| SCHEMBL9518430 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL9518391 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL6155424 | 0.73 | CYP4F2 (0.36) | SLC5A1SLC5A2 | |
| SCHEMBL6157517 | 0.73 | HIF1A (0.35) | PDE10A | |
| SCHEMBL9518297 | 0.71 | — | — | |
| SCHEMBL3745991 | 0.71 | TAAR1 (0.47) | ALDH1A1 | |
| SCHEMBL6189927 | 0.71 | PTGS2 (0.38) | ALDH1A1SLC5A1SLC5A2 | |
| SCHEMBL5534700 | 0.71 | HIF1A (0.32) | PDE10AMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |