Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12496531 | 0.65 | POLB (0.56) | POLBMAPK1HSD17B10HTTPGK1 | |
| SCHEMBL186344 | 0.65 | KMT2A (0.48) | POLBMAPK1HSD17B10HTTPGK1 | |
| SCHEMBL3805546 | 0.64 | HTT (0.45) | POLBMAPK1HSD17B10HTTPGK1 | |
| SCHEMBL2308680 | 0.63 | GOT1 (0.39) | POLBMAPK1HSD17B10 | |
| SCHEMBL2047792 | 0.62 | ALDH1A1 (0.31) | — | |
| SCHEMBL16395567 | 0.62 | HTT (0.38) | POLBMAPK1HSD17B10HTTPGK1 | |
| SCHEMBL20369021 | 0.61 | POLB (0.44) | POLBMAPK1HSD17B10 | |
| SCHEMBL690812 | 0.59 | MAPK1 (1.00) | POLBMAPK1HSD17B10PGK1 | |
| SCHEMBL11475129 | 0.59 | MAOB (0.44) | POLBMAPK1HSD17B10PGK1 | |
| SCHEMBL2178096 | 0.58 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5155861-A | — | — | None | — | — | JP | disclosed |
| JP-H05155861-A | PYRIDAZINE DERIVATIVE, ITS PRODUCTION AND ACARICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SUMITOMO CHEM CO LTD | 1993-06-22 | — | — | JP | disclosed |