SCHEMBL690812

SCHEMBL690812

C#CCOc1nc(OCC#C)nc(OCC#C)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 1.00
POLB P06746 1/20 1.00
HSD17B10 Q99714 1/20 1.00
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOB P27338 8/20 0.38
MAOA P21397 4/20 0.38
ACHE P22303 1/20 0.38
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
MGMT P16455 1/20 0.35
CCNA2 P20248 1/20 0.35
CDK2 P24941 1/20 0.35
CCNA1 P78396 1/20 0.35
CA12 O43570 4/20 0.33
CA9 Q16790 4/20 0.33
CA4 P22748 3/20 0.33
CA1 P00915 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12508379 0.88 MAPK1 (0.77) MAPK1POLBHSD17B10MEN1ALDH1A1
SCHEMBL19724990 0.86 MAPK1 (0.74) MAPK1POLBHSD17B10MEN1ALDH1A1
SCHEMBL10725968 0.82 MAPK1 (0.68) MAPK1POLBHSD17B10MEN1ALDH1A1
SCHEMBL378972 0.82 MAPK1 (0.68) MAPK1POLBHSD17B10MEN1ALDH1A1
SCHEMBL10933335 0.76 MAPK1 (0.61) MAPK1POLBHSD17B10MEN1ALDH1A1
SCHEMBL5793591 0.74 MAPK1 (0.58) MAPK1POLBHSD17B10MEN1ALDH1A1
SCHEMBL12496531 0.72 POLB (0.56) MAPK1POLBHSD17B10MAOBMAOA
SCHEMBL11793023 0.72 MAPK1 (0.53) MAPK1POLBHSD17B10MEN1ALDH1A1
SCHEMBL17198727 0.71 POLB (0.54) MAPK1POLBHSD17B10MAOBMAOA
SCHEMBL17198722 0.71 POLB (0.54) MAPK1POLBHSD17B10MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119456038-A Metalloporphyrin-based flexible conjugated organic polymer-bismuth oxyhalide composite material, preparation method and photocatalytic CO2Reduction application 浙江工业大学 2025-02-18 CN claimed
CN-117089050-A Porphyrin-based flexible conjugated microporous polymer and preparation method and application thereof 浙江工业大学 2023-11-21 CN claimed
US-9126954-B2 Hydroxy group protecting agent and hydroxy group protection method NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2015-09-08 US claimed
US-20140343281-A1 HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2014-11-20 US claimed
CN-119456038-A Metalloporphyrin-based flexible conjugated organic polymer-bismuth oxyhalide composite material, preparation method and photocatalytic CO2Reduction application 浙江工业大学 2025-02-18 CN disclosed
CN-117089050-A Porphyrin-based flexible conjugated microporous polymer and preparation method and application thereof 浙江工业大学 2023-11-21 CN disclosed
US-10774062-B2 Photocuring method, compound and composition used therein FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-09-15 US disclosed
EP-3409709-B1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-08-19 EP disclosed
US-20200234943-A1 Methods For Depositing Blocking Layers On Metal Surfaces APPLIED MATERIALS, INC. 2020-07-23 US disclosed
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-02-21 US disclosed
EP-3409709-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM Wako Pure Chemical Corporation (JP) 2018-12-05 EP disclosed
EP-2781511-B1 HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD UNIV NAT CORP KANAZAWA (JP) 2017-12-20 EP disclosed
US-20090069561-A1 CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2009-03-12 US disclosed
US-20090069561-A1 CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2009-03-12 US disclosed
WO-2007112362-A2 CONSTRUCTION OF A MULTIVALENT SCFV THROUGH ALKYNE-AZIDE 1,3-DIPOLAR CYCLOADDITION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-10-04 WO disclosed
EP-1765910-A2 CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS The Scripps Research Institute (US) 2007-03-28 EP disclosed
WO-2006005046-A9 CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS SCRIPPS RESEARCH INST (US) 2006-03-09 WO disclosed
WO-2006005046-A2 CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2006-01-12 WO disclosed
EP-1208014-B1 POSITIVE ACTING PHOTORESIST COMPOSITION AND IMAGEABLE ELEMENT CREO IL LTD (IL) 2004-04-14 EP disclosed
US-6541181-B1 Heat sensitive element on lithographic substrate CREO IL. LTD. (IL) 2003-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140343281-A1 HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD OGG1, HAO2, HAAO MAPK1 2559/4885POLB 979/4885HSD17B10 126/4885
US-20090069561-A1 CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS CROCC, JAK3, APOBEC3A MAPK1 3690/4885POLB 716/4885HSD17B10 4746/4885
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN ESD, TMT1A, PAM MAPK1 2807/4885POLB 272/4885HSD17B10 1644/4885
US-10774062-B2 Photocuring method, compound and composition used therein ESD, TMT1A, PAM MAPK1 2807/4885POLB 272/4885HSD17B10 1644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.