Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 5/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518580 | 0.90 | MEN1 (0.61) | HDAC1HDAC6CYP2D6AGTR1AGTR2 | |
| SCHEMBL9518750 | 0.82 | HDAC1 (0.69) | RAB9AHDAC1HDAC6CYP2D6AGTR1 | |
| SCHEMBL11746981 | 0.79 | MEN1 (0.77) | RAB9AHRH1CYP2D6KCNH2POLB | |
| SCHEMBL9086870 | 0.74 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL13508735 | 0.74 | AGTR1 (0.72) | RAB9AHRH1CYP2D6KCNH2AGTR1 | |
| SCHEMBL20879390 | 0.74 | HDAC1 (0.81) | HDAC1HDAC6KCNH2AGTR1AGTR2 | |
| SCHEMBL29411886 | 0.74 | AGTR1 (0.76) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL28487275 | 0.74 | AGTR1 (0.76) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL229324 | 0.74 | MEN1 (0.78) | RAB9ACYP2D6AGTR1AGTR2POLB | |
| SCHEMBL15705709 | 0.74 | HDAC1 (0.84) | HDAC1HDAC6KCNH2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | claimed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | claimed |
| EP-0350467-A1 | Pharmacologically active benzimidazole derivatives | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-01-10 | — | — | EP | claimed |
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | disclosed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |