Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518750 | 0.92 | HDAC1 (0.69) | MEN1KMT2ALMNAALDH1A1HDAC1 | |
| SCHEMBL9518397 | 0.90 | RAB9A (0.67) | ALDH1A1HDAC1HDAC6AGTR1AGTR2 | |
| SCHEMBL229324 | 0.84 | MEN1 (0.78) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL28487275 | 0.83 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL29411886 | 0.83 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL15569105 | 0.83 | MEN1 (0.72) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL4952279 | 0.82 | AGTR1 (0.78) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL9740603 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL7545514 | 0.81 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL7545509 | 0.81 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | claimed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | claimed |
| EP-0350467-A1 | Pharmacologically active benzimidazole derivatives | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-01-10 | — | — | EP | claimed |
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | disclosed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |
| EP-0350467-A1 | Pharmacologically active benzimidazole derivatives | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-01-10 | — | — | EP | disclosed |