Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212313 | 0.82 | AOC3 (0.53) | AOC3KDM4ETSHRSMN1; SMN2POLB | |
| SCHEMBL9518445 | 0.79 | IDO1 (0.41) | KDM4ETSHRPOLBGAAMAPT | |
| SCHEMBL6718819 | 0.77 | CA2 (0.47) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL11084282 | 0.75 | ALOX5 (0.47) | CA1CA2CA4CA6AOC3 | |
| SCHEMBL16245173 | 0.74 | AOC3 (0.42) | AOC3KDM4ETSHRSMN1; SMN2POLB | |
| SCHEMBL9109330 | 0.73 | TUBB1 (0.47) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL4369269 | 0.72 | ABCB1 (0.57) | CA1CA2KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL20789931 | 0.71 | CA2 (0.40) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL29800758 | 0.71 | CA2 (0.47) | CA1CA2CA4KDM4ETSHR | |
| SCHEMBL10398173 | 0.71 | CA2 (0.47) | CA1CA2CA4KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |