Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 14/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 12/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519276 | 0.89 | TBXA2R (0.67) | TBXA2RPTGDRPDE2AAKR1B1 | |
| SCHEMBL9521310 | 0.87 | TBXA2R (0.64) | TBXA2RPTGDRPDE2AHDAC6 | |
| SCHEMBL9519669 | 0.81 | TBXA2R (0.56) | TBXA2RPTGDRHTR6PDE2AAKR1B10 | |
| SCHEMBL7248571 | 0.81 | PDE2A (0.68) | TBXA2RPTGDRPDE2AMEN1KMT2A | |
| SCHEMBL9518334 | 0.80 | TBXA2R (0.79) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518784 | 0.80 | TBXA2R (0.54) | TBXA2RPTGDRHTR6AKR1B1 | |
| SCHEMBL9518789 | 0.78 | TBXA2R (0.69) | TBXA2RPTGDRPDE2AAKR1B1 | |
| SCHEMBL9519473 | 0.78 | TBXA2R (0.61) | TBXA2RPTGDRPDE2A | |
| SCHEMBL10582670 | 0.73 | TBXA2R (0.63) | TBXA2RPTGDRPDE2AHDAC6 | |
| SCHEMBL9518426 | 0.72 | TBXA2R (0.63) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |