Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.67 |
| ▸ | PTGDR | Q13258 | 10/20 | 0.51 |
| ▸ | PDE2A | O00408 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519669 | 0.93 | TBXA2R (0.56) | TBXA2RPTGDRPDE2ATBXAS1AKR1B1 | |
| SCHEMBL9518784 | 0.90 | TBXA2R (0.54) | TBXA2RPTGDRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9518525 | 0.89 | TBXA2R (0.52) | TBXA2RPTGDRPDE2AAKR1B1 | |
| SCHEMBL9518789 | 0.89 | TBXA2R (0.69) | TBXA2RPTGDRPDE2AKDM4ECYP1A2 | |
| SCHEMBL9521310 | 0.87 | TBXA2R (0.64) | TBXA2RPTGDRPDE2A | |
| SCHEMBL7248571 | 0.85 | PDE2A (0.68) | TBXA2RPTGDRPDE2ACYP3A4MAPT | |
| SCHEMBL9518426 | 0.83 | TBXA2R (0.63) | TBXA2RPTGDRPDE2AKDM4ECYP1A2 | |
| SCHEMBL10588990 | 0.80 | TBXA2R (0.67) | TBXA2RPTGDRPDE2AKDM4ECYP1A2 | |
| SCHEMBL9277313 | 0.80 | TBXA2R (1.00) | TBXA2RPTGDRPDE2APTGER3PTGER2 | |
| SCHEMBL9518281 | 0.79 | TBXA2R (0.82) | TBXA2RPTGDRPDE2APTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |