Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519276 | 0.90 | TBXA2R (0.67) | TBXA2RTBXAS1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL9519669 | 0.90 | TBXA2R (0.56) | TBXA2RTBXAS1HTR6HRH1PTGDR | |
| SCHEMBL9519724 | 0.82 | TBXA2R (0.79) | TBXA2RTBXAS1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9518789 | 0.81 | TBXA2R (0.69) | TBXA2RTBXAS1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL9518525 | 0.80 | TBXA2R (0.52) | TBXA2RHTR6PTGDRAKR1B1 | |
| SCHEMBL9518277 | 0.79 | TBXA2R (0.64) | TBXA2RTBXAS1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9521310 | 0.77 | TBXA2R (0.64) | TBXA2RPTGDR | |
| SCHEMBL9518426 | 0.77 | TBXA2R (0.63) | TBXA2RTBXAS1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7248571 | 0.76 | PDE2A (0.68) | TBXA2RCYP3A4CYP2C9CYP2C19PTGDR | |
| SCHEMBL9518398 | 0.75 | PTGDR (0.48) | TBXA2RPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |