Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518641 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL11116397 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MAPK1KMT2AAKT1HTR2A | |
| SCHEMBL11113755 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPK1KMT2AAKT1HTR2A | |
| SCHEMBL1005341 | 0.76 | HTR2A (0.51) | AKT1HTR2ASIRT2 | |
| SCHEMBL12191290 | 0.74 | HTR1A (0.37) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL30888630 | 0.73 | AKT1 (0.42) | AKT1HTR2ASIRT2 | |
| SCHEMBL8387152 | 0.72 | TSHR (0.43) | SIRT2 | |
| SCHEMBL2616011 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL14041574 | 0.71 | ALDH1A1 (0.35) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL11114171 | 0.70 | ALOX15 (0.35) | ALDH1A1MAPK1KMT2AAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |