Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517509 | 0.86 | POLB (0.40) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL9517484 | 0.83 | CES2 (0.35) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL13707877 | 0.82 | POLB (0.51) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL11219371 | 0.80 | TSHR (0.35) | POLBHPGDMAPTTSHRSMN1; SMN2 | |
| SCHEMBL10577634 | 0.80 | POLB (0.46) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL8055152 | 0.78 | POLB (0.55) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL9516579 | 0.78 | PLAU (0.34) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL9186662 | 0.77 | POLB (0.47) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL3820327 | 0.76 | POLB (0.53) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL32668944 | 0.76 | KEAP1 (0.55) | POLBAPEX1HPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411252-B1 | Process for the preparation of fluorobenzoic acids | RIEDEL DE HAEN AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-5093529-A | Process for the preparation of fluorinated benzoic acids | CASSELLA AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0411252-A1 | Process for the preparation of fluorobenzoic acids | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1991-02-06 | — | — | EP | disclosed |