Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537172 | 1.00 | CYP1A2 (0.75) | CYP1A2KDM4EHPGDCYP2C19MEN1 | |
| Cyclopropane SCHEMBL29022116 | 0.94 | CYP1A2 (0.68) | CYP1A2KDM4EHPGDCYP2C19MEN1 | |
| Dimethylformamide SCHEMBL11044579 | 0.86 | CYP1A2 (0.58) | CYP1A2KDM4EHPGDCYP2C19MEN1 | |
| SCHEMBL2068768 | 0.85 | LMNA (0.68) | CYP1A2KDM4EHPGDMEN1KMT2A | |
| SCHEMBL29840068 | 0.85 | GAA (0.67) | CYP1A2KDM4EHPGDMEN1KMT2A | |
| SCHEMBL3928666 | 0.85 | GAA (0.67) | CYP1A2KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6859262 | 0.84 | CYP1A2 (0.64) | CYP1A2KDM4EHPGDCYP2C19MEN1 | |
| SCHEMBL10458447 | 0.84 | KDM4E (0.72) | CYP1A2KDM4EHPGDCYP2C19MEN1 | |
| SCHEMBL4359338 | 0.84 | CYP1A2 (0.56) | CYP1A2KDM4EHPGDCYP2C19MEN1 | |
| SCHEMBL4107106 | 0.83 | CYP1A2 (0.70) | CYP1A2KDM4EHPGDCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198426-B2 | Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-2836485-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | Polyphor Ag (CH) | 2015-02-18 | — | — | EP | claimed |
| WO-2013139697-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2013-09-26 | — | — | WO | claimed |
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER CORPSCIENCE AG (DE) | 2010-07-01 | — | — | US | claimed |
| EP-2198710-A1 | Use of 5-pyridin-4yl-(1,3) thiazoles for combating phytopathogenic fungi | Bayer CropScience AG (DE) | 2010-06-23 | — | — | EP | claimed |
| CN-100389104-C | Process for preparation of 2,6-dichloroaniline | UNIV ZHEJIANG (CN) | 2008-05-21 | — | — | CN | claimed |
| CN-1942475-A | Substituted thieno - and thiazolo - [2, 3-d] pyridines as inhibitors of Tie2 | ASTRAZENECA AB (SE) | 2007-04-04 | — | — | CN | claimed |
| EP-1737830-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | claimed |
| EP-1716155-A1 | SUBSTITUTED THIENO¬2,3-D|PYRIMIDINES AS INHIBITORS OF TIE2 | AstraZeneca AB (SE) | 2006-11-02 | — | — | EP | claimed |
| CN-1827584-A | Process for preparation of 2,6-dichloroaniline | UNIV ZHEJIANG (CN) | 2006-09-06 | — | — | CN | claimed |
| WO-2005105757-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-10 | — | — | WO | claimed |
| EP-1578751-A1 | PYRROLOPYRIMIDINE DERIVATIVES | Pfizer Products Inc. (US) | 2005-09-28 | — | — | EP | claimed |
| WO-2005075483-A1 | SUBSTITUTED THIENO - AND THIAZOLO - [2, 3-D] PYRIDINES AS INHIBITORS OF TIE2 | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | claimed |
| WO-2004056830-A1 | PYRROLOPYRIMIDINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2004-07-08 | — | — | WO | claimed |
| JP-62018460-A | — | — | None | — | — | JP | disclosed |
| US-12378354-B2 | Active ester resin, method for producing thereof, epoxy resin composition, cured product thereof, prepreg, laminated board, and material for circuit substrate | NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) | 2025-08-05 | — | — | US | disclosed |
| CN-119948080-A | Active ester resin, epoxy resin composition, cured product thereof, prepreg, laminated board and laminated film | 日铁化学材料株式会社 | 2025-05-06 | — | — | CN | disclosed |
| CN-85108862-A | The preparation method and the application thereof of N-(3-chloro-1,2,4- diazole-5-yl) urea | — | 1986-07-30 | — | — | CN | disclosed |
| EP-0182166-A2 | Process for preparing phenylisopropylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1986-05-28 | — | — | EP | disclosed |
| US-4578513-A | Process for preparing phenylisopropylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | PIR, PNPO, PDXK | CYP1A2 1420/4885KDM4E 941/4885HPGD 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.