SCHEMBL951969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3902972	0.87	CYP19A1 (0.50)	CYP19A1EPHX2CYP17A1NPSR1TSHR
	SCHEMBL12914680	0.87	TSHR (0.56)	CYP19A1EPHX2CYP17A1NPSR1TSHR
	SCHEMBL950538	0.85	ALDH1A1 (0.39)	CYP19A1EPHX2NPSR1LMNAALDH1A1
	SCHEMBL951987	0.84	CYP19A1 (0.49)	CYP19A1EPHX2CYP17A1NPSR1TSHR
	SCHEMBL950229	0.83	EPHX2 (0.31)	CYP19A1EPHX2
	SCHEMBL952296	0.83	CYP19A1 (0.44)	CYP19A1EPHX2CYP17A1NPSR1TSHR
	SCHEMBL12914672	0.80	—	—
	SCHEMBL24361158	0.79	CYP19A1 (0.44)	CYP19A1EPHX2CYP17A1NPSR1TSHR
	SCHEMBL953363	0.79	TSHR (0.41)	CYP19A1EPHX2CYP17A1NPSR1TSHR
	SCHEMBL18776034	0.79	CYP19A1 (0.41)	CYP19A1EPHX2CYP17A1NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.