Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002776 | 0.88 | ALOX5 (0.67) | CYP19A1CYP3A4CYP1A2TSHRNFKB1 | |
| Zingerone SCHEMBL14763994 | 0.87 | ALOX5 (0.74) | CYP3A4CYP1A2TSHRNFKB1LMNA | |
| Zingerone SCHEMBL29828498 | 0.87 | ALOX5 (0.74) | CYP3A4CYP1A2TSHRNFKB1LMNA | |
| SCHEMBL490726 | 0.87 | GAA (0.71) | CYP19A1CYP3A4CYP1A2TSHRNFKB1 | |
| Zingerone SCHEMBL29378477 | 0.87 | ALOX5 (0.74) | CYP3A4CYP1A2TSHRNFKB1LMNA | |
| Zingerone SCHEMBL119051 | 0.87 | ALOX5 (0.74) | CYP3A4CYP1A2TSHRNFKB1LMNA | |
| SCHEMBL31337638 | 0.87 | GAA (0.71) | CYP19A1CYP3A4CYP1A2TSHRNFKB1 | |
| SCHEMBL269005 | 0.86 | NPC1 (0.61) | CYP19A1CYP3A4CYP1A2LMNANPC1 | |
| SCHEMBL6339281 | 0.85 | ALOX5 (0.77) | CYP19A1CYP3A4CYP1A2TSHRNFKB1 | |
| SCHEMBL28287006 | 0.85 | CYP19A1 (0.65) | CYP19A1CYP3A4CYP1A2TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |
| EP-2624808-B1 | USE OF SUBSTITUTED METHOXYALKOXYPHENYLALKYL DERIVATIVES AS PRESERVATIVE, PRESERVING METHOD, COMPOUNDS AND COMPOSITION | L'ORÉAL (FR) | 2017-03-22 | — | — | EP | disclosed |
| US-9381143-B2 | Use of substituted methoxyalkoxyphenylalkyl derivatives as preservative, preserving method, compounds and composition | L'OREAL (FR) | 2016-07-05 | — | — | US | disclosed |
| US-20130230473-A1 | USE OF SUBSTITUTED METHOXYALKOXYPHENYLALKYL DERIVATIVES AS PRESERVATIVE, PRESERVING METHOD, COMPOUNDS AND COMPOSITION | L'OREAL (FR) | 2013-09-05 | — | — | US | disclosed |
| EP-0316790-B1 | RHODANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-4897406-A | CHEMICAL MEDIATOR INHIBITORS INCLUDING LEUKOTRIENES; ANTIALLERGENS; BRONCHODILATOR AND ANTIICHEMIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130230473-A1 | USE OF SUBSTITUTED METHOXYALKOXYPHENYLALKYL DERIVATIVES AS PRESERVATIVE, PRESERVING METHOD, COMPOUNDS AND COMPOSITION | H1-0, H1-3, C9 | CYP19A1 79/4885CYP3A4 738/4885CYP1A2 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.