SCHEMBL951986

SCHEMBL951986

CC(C)/C=C/CCCCC=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 5/20 0.50
FAAH O00519 2/20 0.50
TSHR P16473 3/20 0.44
HIF1A Q16665 1/20 0.43
MAPT P10636 3/20 0.35
ALDH1A1 P00352 4/20 0.33
CYP3A4 P08684 4/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
USP2 O75604 1/20 0.33
RECQL P46063 1/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM1A O60341 1/20 0.33
NR1I2 O75469 1/20 0.33
ALOX5 P09917 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ALOX15 P16050 1/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6058525 1.00 TRPV1 (0.50) TRPV1FAAHTSHRHIF1AMAPT
SCHEMBL28245143 0.80 TRPV1 (0.36) TRPV1FAAHMAPTALDH1A1CYP3A4
SCHEMBL28151994 0.77 MEN1 (0.50) TRPV1FAAHTSHRMAPTALDH1A1
SCHEMBL73315 0.77 MEN1 (0.50) TRPV1FAAHTSHRMAPTALDH1A1
SCHEMBL73313 0.77 MEN1 (0.50) TRPV1FAAHTSHRMAPTALDH1A1
SCHEMBL4284074 0.75 SPHK2 (0.37) TRPV1MAPTALDH1A1CYP3A4LMNA
SCHEMBL5613599 0.75 MEN1 (0.53) TRPV1FAAHMAPTALDH1A1CYP3A4
SCHEMBL5613640 0.75 MEN1 (0.53) TRPV1FAAHMAPTALDH1A1CYP3A4
SCHEMBL5613660 0.75 MEN1 (0.53) TRPV1FAAHMAPTALDH1A1CYP3A4
SCHEMBL2004490 0.75 MEN1 (0.53) TRPV1FAAHMAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9801850-B2 Antibacterial agent OSAKA UNIVERSITY (JP) 2017-10-31 US claimed
EP-2460405-B1 EPIGALLOCATECHIN GALLATE DERIVATIVE AS ANTIBACTERIAL AGENT UNIV OSAKA (JP) 2015-03-18 EP claimed
EP-2460405-A1 ANTIBACTERIAL AGENT Osaka University (JP) 2012-06-06 EP claimed
US-20120136049-A1 ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2012-05-31 US claimed
WO-2022132902-A1 CAPSAICIN AND TRPV1 MODULATOR COMPOSITIONS AND METHODS OF USE THEREOF PANO THERAPEUTICS, INC. (US) 2022-06-23 WO disclosed
WO-2020252046-A1 CAPSAICIN AND TRPV1 MODULATOR COMBINATIONS AND METHODS OF USE THEREOF PANO THERAPEUTICS, INC. (US) 2020-12-17 WO disclosed
US-9901565-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2018-02-27 US disclosed
US-9801850-B2 Antibacterial agent OSAKA UNIVERSITY (JP) 2017-10-31 US disclosed
US-20150111961-A1 MEMBRANE FUSION INHIBITOR PROTECTEA, LTD. (JP) 2015-04-23 US disclosed
EP-2460405-B1 EPIGALLOCATECHIN GALLATE DERIVATIVE AS ANTIBACTERIAL AGENT UNIV OSAKA (JP) 2015-03-18 EP disclosed
US-8952055-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2015-02-10 US disclosed
EP-2460405-A1 ANTIBACTERIAL AGENT Osaka University (JP) 2012-06-06 EP disclosed
US-20120136049-A1 ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2012-05-31 US disclosed
US-20110003889-A1 MEMBRANE FUSION INHIBITOR KAIHATSU, Kunihiro (JP) 2011-01-06 US disclosed
EP-1069105-B1 CAPSAICINOIDE-LIKE SUBSTANCES HAVING ESTER BOND AJINOMOTO KK (JP) 2007-09-19 EP disclosed
US-6333421-B1 SUBSTANCES HAVING IMMUNOPOTENTIATING AND ENERGY METABOLISM ENHANCING ACTIVITY MORINAGA & CO., LTD. (JP) 2001-12-25 US disclosed
EP-1069105-A1 NOVEL CAPSAICINOIDE-LIKE SUBSTANCES HAVING ESTER BOND MORINAGA & CO., LTD. (JP) 2001-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136049-A1 ANTIBACTERIAL AGENT TEAD4, ELOVL6, TEAD1 TRPV1 734/4885FAAH 2034/4885TSHR 2877/4885
US-20150111961-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 TRPV1 764/4885FAAH 519/4885TSHR 2134/4885
US-20110003889-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 TRPV1 764/4885FAAH 519/4885TSHR 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.